Grade 2 gliomas are malignant brain tumours affecting otherwise healthy adults. Although the long-term prognosis is poor, many patients are well and may have a high quality of life for several years. There is, however, a large variability in the natural course of the disease which makes it essential to identify patients who might benefit [...]
Segmentation and Analysis of Volume Images, with Applications
Digital image analysis is the field of extracting relevant information from digital images. Recent developments in imaging techniques have made 3-dimensional volume images more common. This has created a need to extend existing 2D image analysis tools to handle images of higher dimensions. Such extensions are usually not straightforward. In many cases, the theoretical and [...]
Synthesis, Characterisation and Application of 68Ga-labelled Macromolecules
The positron emitting radionuclide 68Ga (T1/2 = 68 min) might become of practical interest for clinical positron emission tomography (PET). The metallic cation, 68Ga(III), is suitable for complexation with chelators, either naked or conjugated with biological macromolecules. Such labelling procedures require pure and concentrated preparations of 68Ga(III), which cannot be sufficiently fulfilled by the presently [...]