Electrospray ionization (ESI) mass spectrometry (MS) in combination with liquid chromatography (LC) is an excellent tool for the identification of drug metabolites. Utilizing this hyphenated strategy in conjunction with proper example pretreatment, the metabolic pathways of this analgesic drug ketobemidone
Structure and Activity of Circular Plant Proteins: Cytotoxic Effects of Viola Cyclotides
Cyclotides are a family of small and macrocyclic proteins that have been found in Violacaee and Rubiaceae plant species. These proteins contain a cystine knot: two disulfides bonds together with their connecting peptide backbone form an embedded ring which is penetrated by a third disulfide bond. The cyclotides have been attributed a wide range of [...]