Analysis of the chemical/biological species involved in health care is the most important step for diseases diagnosis and new drug screening. Barcoded nano/microparticles are attracting more and more interest for detection and identification of multiplexed chemical/biological species simultaneously. However, the development of barcoded particles is still in an early stage… Contents Chapter 1 Scientific Background [...]
Biological Sensing and DNA Templated Electronics Using Conjugated Polymers
Conjugated polymers have been found useful in a wide range of applications such as solar cells, sensor elements and printed electronics, due to their optical and electronic properties. Functionalization with charged side chains has enabled water solubility, resulting in an enhanced interaction with biomolecules. This thesis focus on the emerging research fields, where these conjugated [...]
Modifying Polydimethylsiloxane (PDMS) surfaces
The aim of the project was to modify polydimethylsiloxane (PDMS) surfaces in order to minimize adsorption of proteins. PDMS is used in micro-fluidic devices that control the delivery of samples to a sensor chip in Biacore instrumentation. These instruments are used to characterize interactions between biomolecules with a detection principle based on surface plasmon resonance [...]