A Riemannian manifold is a mathematical concept that generalizes curved surfaces to higher dimensions, giving a precise meaning to concepts like angle, length, area, volume and curvature. A glimpse of the consequences of a non-flat geometry is given on the sphere, where the shortest path between two points – a geodesic – is along a [...]
Biomedical Engineering Projects
Biomedical engineering is the application of engineering principles and design concepts to medicine and biology. This field seeks to close the gap between engineering and medicine. This section is dedicated to biomedical engineering projects, biomedical project ideas, biological engineering projects, biotechnological engineering final year projects, biomedical engineering project sample, bioengineering project topics, biomedical engineering project list.
Biological Sensing and DNA Templated Electronics Using Conjugated Polymers
Conjugated polymers have been found useful in a wide range of applications such as solar cells, sensor elements and printed electronics, due to their optical and electronic properties. Functionalization with charged side chains has enabled water solubility, resulting in an enhanced interaction with biomolecules. This thesis focus on the emerging research fields, where these conjugated [...]
Investigation of transmural cardiac and fiber strain in ischemic and non-ischemic tissue during diastole
The cardiac wall has complex three-dimensional fiber structures and mechanical properties that enable the heart to efficiently pump the blood through the body. By studying the myocardial strains induced during diastole, information about the pumping performance of the heart and what mechanisms that are responsible for this effective blood filling, can be achieved. Two different [...]
The influence of Ca2+ and Nitroprusside on the opening kinematics of the mitral valve
During a cardiac cycle the cardiac walls change between contracted and relaxed and the valves open and close in response to pressure changes. This master thesis is a study of the changes in heart movement pattern caused by intravenous injections of Ca2+ or Nitroprusside. At Stanford University radiopaque markers have been surgically implanted in the [...]
Modifying Polydimethylsiloxane (PDMS) surfaces
The aim of the project was to modify polydimethylsiloxane (PDMS) surfaces in order to minimize adsorption of proteins. PDMS is used in micro-fluidic devices that control the delivery of samples to a sensor chip in Biacore instrumentation. These instruments are used to characterize interactions between biomolecules with a detection principle based on surface plasmon resonance [...]
Affinity Determination of Protein A Domains to IgG subclasses by Surface Plasmon Resonance
A capture step with protein A is the most common purification step in the downstream purification process of monoclonal antibodies. It is therefore of great importance to increase the knowledge of the interactions involved in this purification technique. The purpose of this master thesis project was to determine the affinity of protein A domains to [...]
Enhanced amyloid fibril formation of insulin in contact with catalytic hydrophobic surfaces
The important protein hormone insulin, responsible for different kind of functions in our body but mainly storage of nutrients, has for a long time been used for treatment of diabetic patients. This important protein is both physically and chemically unstable. Especially during production where the insulin protein is exposed to unnatural environmental conditions such as [...]
Neural Network Gaze Tracking using Web Camera
Gaze tracking means to detect and follow the direction in which a person looks. This can be used in for instance human-computer interaction. Most existing systems illuminate the eye with IR-light, possibly damaging the eye. The motivation of this thesis is to develop a truly non-intrusive gaze tracking system, using only a digital camera, e.g. [...]
On optical methods for intracerebral measurements during stereotactic and functional neurosurgery: Experimental studies
Radio frequency (RF) lesioning and deep brain stimulation (DBS) are the two prevailing surgical treatments for movement disorders within the field of stereotactic and functional neurosurgery. For RF-lesioning, a small volume of brain tissue is coagulated and knowledge of the lesion size and growth is of great importance for the safety and outcome of the [...]